Basic Information
ID: ALA5156002
Type: Functional
Description: Induction of mitochondrial membrane potential loss in human multi-drug resistant NCI-H460/R cells overexpressing P-glycoprotein assessed as depolarization of mitochondrial membrane at 600 nM incubated for 24 hrs by JC-1 staining based flow cytometry assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: NCI-H460
Target: NCI-H460(ALA396)
Document: ALA5154660
Induction of mitochondrial membrane potential loss in human multi-drug resistant NCI-H460/R cells overexpressing P-glycoprotein assessed as depolarization of mitochondrial membrane at 600 nM incubated for 24 hrs by JC-1 staining based flow cytometry assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5156002
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 547.52 | 6.80 | 6.80 |
| 591.53 | 6.53 | 6.53 |