Basic Information
ID: ALA5156182
Type: Binding
Description: Inhibition of Cy3-labeled mouse preE-let-7f-1 miRNA binding to human LIN28A (16 to 187 residues) expressed in Escherichia coli BL21 (DE3) at 75 uM preincubated for 2 hrs followed by miRNA addition and measured after 15 mins by electrophoretic mobility shift assay relative to control
Format: BAO_0000019
Target: Unchecked(ALA612545)
Document: ALA5154666
Inhibition of Cy3-labeled mouse preE-let-7f-1 miRNA binding to human LIN28A (16 to 187 residues) expressed in Escherichia coli BL21 (DE3) at 75 uM preincubated for 2 hrs followed by miRNA addition and measured after 15 mins by electrophoretic mobility shift assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5156182
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 335.40 | 4.61 | 4.61 |
| 349.43 | 5.00 | 5.00 |
| 349.43 | 4.70 | 4.70 |
| 287.36 | 3.10 | 3.10 |
| 333.39 | 4.41 | 4.41 |
| 316.36 | 4.08 | 4.08 |
| 321.38 | 4.22 | 4.22 |
| 381.43 | 4.24 | 4.24 |
| 359.39 | 5.93 | 5.93 |
| 307.39 | 4.62 | 4.62 |
| 316.40 | 4.78 | 4.78 |
| 360.24 | 5.52 | 5.52 |
| 333.39 | 4.41 | 4.41 |
| 336.39 | 4.82 | 4.82 |
| 335.40 | 4.61 | 4.61 |
| 292.38 | 4.31 | 4.31 |
| 259.31 | 2.62 | 2.62 |