Basic Information
ID: ALA5156315
Type: Binding
Description: Inhibition of (S)-3-(3-(5-acrylamido-6-(3-(5-(2-methyl-5-(3-(trifluoromethyl)benzamido)benzamido)pyrimidin-2-ylamino)phenylamino)-6-oxohexylamino)-3-oxopropyl)-5,5-difluoro-7,9-dimethyl-5H-dipyrrolo[1,2-c:1',2'-f][1,3,2]diazaborinin-4-ium-5-uide binding to BTK in human NAMALVA cells at higher concentration preincubated for 1 hr followed by compound washout for three times and treated with probe for 1 hr by competitive labeling assay
Organism: Homo sapiens
Cell type: NAMALVA
Activity Charts
Bioactivity
Activity Types for Assay ALA5156315
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 683.82 | 6.10 | 6.10 |
| 626.72 | 6.17 | 6.17 |