Basic Information
ID: ALA5156584
Type: Binding
Description: Binding affinity to His6-tagged human SMARCA2 bromodomain (1367 to 1511 residues) expressed in Escherichia coli BL21 (DE3) assessed as increase in thermal stability by measuring change in melting temperature at 200 uM incubated for 30 mins by SYPRO orange dye based thermal shift assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5156584
Delta Tm
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 386.46 | 3.78 | 3.78 |
| 534.61 | 6.97 | 6.97 |
| 476.51 | 4.79 | 4.79 |
| 421.43 | 3.01 | 3.01 |
| 519.53 | 4.28 | 4.28 |
| 461.50 | 4.37 | 4.37 |