Assay Report Card

Basic Information

ID: ALA5156825

Type: Functional

Description: Neuroprotective activity against ethacrynic acid-induced neurotoxicity human SH-SY5Y cells assessed as decrease in TDP-43 phosphorylation at Ser409 at 5 uM preincubated for 1 hr followed by EA addition and further incubated for 24 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: SH-SY5Y

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
316.364.804.80
336.785.155.15
336.785.155.15