Assay Report Card

Basic Information

ID: ALA5156827

Type: Binding

Description: Inhibition of recombinant human TTBK1 in ethacrynic acid-treated human SH-SY5Y cells assessed as nuclear localization by measuring reduction in cytosolic TDP-43 accumulation at 5 uM preincubated for 1 hr followed by EA addition and further incubated for 24 hrs by confocal laser scanning microscopy

Organism: Homo sapiens

Cell type: SH-SY5Y

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
336.785.155.15