Assay Report Card

Basic Information

ID: ALA5157325

Type: Functional

Description: Anti-NASH activity against high fat (HF) diet-induced nonalcoholic steatohepatitis in leptin-deficient ob/ob mouse model assessed as reduction in liver cholesterol level at 3 mg/kg, po administered once daily from week 5 to 10

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
549.417.587.58
523.377.097.09
535.387.867.86
537.407.657.65