Basic Information
ID: ALA5157443
Type: Binding
Description: Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 mins followed by substrate addition and measured after 15 mins by liquid scintillation counting analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5157443
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 370.41 | 4.73 | 4.73 |
| 463.49 | 5.85 | 5.85 |
| 433.47 | 5.84 | 5.84 |
| 447.50 | 5.86 | 5.86 |
| 385.42 | 4.81 | 4.81 |
| 463.49 | 5.64 | 5.64 |
| 413.48 | 5.59 | 5.59 |
| 513.35 | 6.44 | 6.44 |
| 512.36 | 6.39 | 6.39 |
| 433.47 | 5.84 | 5.84 |
| 386.41 | 4.86 | 4.86 |
| 428.49 | 6.03 | 6.03 |
| 386.41 | 4.85 | 4.85 |
| 434.45 | 5.89 | 5.89 |
| 399.45 | 4.83 | 4.83 |
| 464.48 | 5.69 | 5.69 |
| 400.44 | 5.25 | 5.25 |
| 413.48 | 5.22 | 5.22 |
| 509.57 | 7.51 | 7.51 |
| 477.52 | 5.87 | 5.87 |
| 510.55 | 7.56 | 7.56 |
| 447.50 | 5.86 | 5.86 |
| 441.53 | 6.00 | 6.00 |
| 434.45 | 5.89 | 5.89 |
| 427.51 | 5.98 | 5.98 |
| 358.35 | 4.08 | 4.08 |
| 479.45 | 5.59 | 5.59 |
| 447.50 | 5.86 | 5.86 |
| 427.51 | 5.61 | 5.61 |
| 433.47 | 5.84 | 5.84 |
| 478.47 | 5.54 | 5.54 |
| 434.45 | 5.89 | 5.89 |
| 414.46 | 5.64 | 5.64 |
| 523.59 | 7.53 | 7.53 |
| 399.45 | 5.20 | 5.20 |
| 464.48 | 5.90 | 5.90 |
| 399.45 | 4.83 | 4.83 |