Basic Information
ID: ALA5157466
Type: Binding
Description: Inhibition of URAT1 R477K mutant (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 mins followed by substrate addition and measured after 15 mins by liquid scintillation counting analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5157466
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 370.41 | 4.73 | 4.73 |
| 433.47 | 5.84 | 5.84 |