Basic Information
ID: ALA5157583
Type: Binding
Description: Inhibition of KRAS G12C mutant (unknown origin) assessed as inhibition of SOS1-catalyzed nucleotide exchange measured by HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5157583
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 560.61 | 4.48 | 4.48 |
| 651.22 | 5.11 | 5.11 |
| 667.26 | 5.75 | 5.75 |
| 653.23 | 5.36 | 5.36 |
| 639.20 | 5.11 | 5.11 |
| 625.18 | 4.72 | 4.72 |