Assay Report Card

Basic Information

ID: ALA5157751

Type: Binding

Description: Inhibition of HDAC1/HDAC2/HDAC3 in human HCT-116 cells assessed as increase in accumulation of acetylated H3K9 at 5 uM preincubated for 6 hrs followed by compound washout and measured up to 48 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: HCT-116

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
376.423.343.34
407.873.403.40
449.954.574.57