Basic Information
ID: ALA5157993
Type: ADME
Description: Microsomal stability in mouse microsomes assessed as parent compound remaining at 1 uM preincubated for 5 mins followed by addition of NADPH regenerating system measured after 30 mins by LC-MS/MS analysis
Organism: Mus musculus
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5157993
Stability
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 398.44 | 3.57 | 3.57 |
| 482.44 | 4.26 | 4.26 |
| 350.42 | 3.16 | 3.16 |
| 448.89 | 3.89 | 3.89 |
| 418.54 | 4.27 | 4.27 |
| 436.87 | 4.12 | 4.12 |
| 419.48 | 3.73 | 3.73 |
| 439.45 | 3.11 | 3.11 |
| 356.36 | 2.45 | 2.45 |
| 431.50 | 3.20 | 3.20 |
| 450.90 | 4.51 | 4.51 |
| 404.51 | 3.88 | 3.88 |
| 448.89 | 3.89 | 3.89 |
| 404.51 | 4.18 | 4.18 |
| 414.44 | 3.24 | 3.24 |
| 474.48 | 4.35 | 4.35 |
| 427.30 | 3.30 | 3.30 |
| 348.41 | 2.54 | 2.54 |
| 368.82 | 3.10 | 3.10 |
| 402.38 | 3.47 | 3.47 |
| 435.26 | 3.21 | 3.21 |
| 390.49 | 3.79 | 3.79 |
| 406.49 | 3.33 | 3.33 |
| 404.51 | 3.84 | 3.84 |
| 484.45 | 4.87 | 4.87 |
| 336.39 | 3.07 | 3.07 |
| 432.57 | 4.66 | 4.66 |
| 418.54 | 4.57 | 4.57 |
| 404.51 | 3.84 | 3.84 |
| 476.50 | 4.96 | 4.96 |
| 415.29 | 3.83 | 3.83 |
| 378.47 | 3.72 | 3.72 |
| 412.47 | 3.75 | 3.75 |
| 440.52 | 4.53 | 4.53 |
| 433.51 | 3.82 | 3.82 |
| 412.47 | 3.75 | 3.75 |
| 478.95 | 5.29 | 5.29 |
| 362.43 | 3.01 | 3.01 |
| 400.45 | 4.02 | 4.02 |
| 442.94 | 4.60 | 4.60 |
| 464.93 | 4.90 | 4.90 |
| 428.92 | 4.21 | 4.21 |
| 426.50 | 4.14 | 4.14 |
| 414.48 | 4.37 | 4.37 |
| 456.97 | 4.99 | 4.99 |
| 440.93 | 3.98 | 3.98 |
| 376.46 | 3.40 | 3.40 |
| 351.41 | 2.55 | 2.55 |
| 359.36 | 2.46 | 2.46 |
| 440.93 | 3.98 | 3.98 |
| 386.43 | 3.63 | 3.63 |