Assay Report Card

Basic Information

ID: ALA5158484

Type: Binding

Description: Inhibition of 6-His tagged-G4SG4 fused ZIKV NS2B (49 to 95 residues) R95A mutant-NS3 (1 to 170 residue) R29G mutant expressed in Escherichia coli BL21 (DE3) assessed as covalent adduct formation using Bz-Nle-K-RR-AMC substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by LC-HRMS analysis

Organism: Zika virus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
712.814.014.01
712.814.014.01