Assay Report Card

Basic Information

ID: ALA5158695

Type: Functional

Description: Anti-fibrotic activity in mouse TCMK-1 cells assessed as inhibition of TGF-beta1 induced fibronectin mRNA expression at 62.5 to 250 nM starved for 24 hrs preincubated with TGFbeta-1 for 24 hrs followed by compound addition measured by RT-PCR analysis

Organism: Mus musculus

Cell type: TCMK-1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
356.433.003.00