Basic Information
ID: ALA5158734
Type: Binding
Description: Inhibition of mPGES-1 activity in IL-1beta human A549 microsomal preparation at 10 uM using PGH2 as substrate preincubated for 15 mins followed by substrate addition for 1 min by RP-HPLC analysis
Organism: Homo sapiens
Cell type: A549
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5158734
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 374.43 | 4.19 | 4.19 |
| 368.40 | 4.86 | 4.86 |
| 383.41 | 4.44 | 4.44 |
| 430.49 | 5.53 | 5.53 |
| 399.48 | 5.26 | 5.26 |
| 400.46 | 5.52 | 5.52 |
| 375.42 | 3.58 | 3.58 |
| 397.44 | 4.90 | 4.90 |
| 374.43 | 4.19 | 4.19 |
| 401.45 | 4.92 | 4.92 |
| 422.49 | 5.31 | 5.31 |