Basic Information
ID: ALA5158735
Type: Binding
Description: Inhibition of mPGES-1 activity in human A549 microsomal preparation using PGH2 as substrate preincubated for 15 mins followed by substrate addition for 1 min by RP-HPLC analysis
Organism: Homo sapiens
Cell type: A549
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5158735
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 414.49 | 5.53 | 5.53 |
| 421.45 | 5.37 | 5.37 |
| 400.46 | 5.52 | 5.52 |
| 414.49 | 6.22 | 6.22 |
| 403.46 | 5.23 | 5.23 |
| 386.44 | 5.73 | 5.73 |
| 414.49 | 5.45 | 5.45 |