Basic Information
ID: ALA5158739
Type: Binding
Description: Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as inhibition of FLAP-dependent 5-LO product LTB4 formation preincubated for 15 mins followed by arachidonic acid addition and measured after 10 mins by RP-HPLC analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5158739
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 400.46 | 5.52 | 5.52 |
| 414.49 | 6.22 | 6.22 |
| 386.44 | 5.73 | 5.73 |