Basic Information
ID: ALA5158741
Type: Binding
Description: Inhibition of 5-LOX in human neutrophils assessed as reduction in FLAP-dependent 5-LO product LTB4 formation at upto 10 uM preincubated for 10 mins followed by A23187 addition and measured after 10 mins by RP-HPLC and UV detection method
Organism: Homo sapiens
Cell type: Neutrophil
Activity Charts
Bioactivity
Activity Types for Assay ALA5158741
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 400.46 | 5.52 | 5.52 |
| 414.49 | 6.22 | 6.22 |
| 386.44 | 5.73 | 5.73 |