Basic Information
ID: ALA5158761
Type: Binding
Description: Inhibition of human ABCG2 in human R5 cells assessed as inhibition of mitoxantrone efflux at 10 uM measured by flow cytometric analysis relative to control
Organism: Homo sapiens
Cell type: R5
Activity Charts
Bioactivity
Activity Types for Assay ALA5158761
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 522.61 | 3.33 | 3.33 |
| 425.90 | 2.92 | 2.92 |
| 574.56 | 2.64 | 2.64 |
| 574.56 | 2.64 | 2.64 |
| 691.67 | 3.53 | 3.53 |
| 709.66 | 3.67 | 3.67 |
| 395.80 | 3.38 | 3.38 |
| 574.56 | 2.64 | 2.64 |
| 623.13 | 4.15 | 4.15 |
| 564.98 | 2.80 | 2.80 |
| 727.65 | 3.81 | 3.81 |