Assay Report Card

Basic Information

ID: ALA5159470

Type: Functional

Description: In vivo inhibition of ATR in human LoVo cells xenografted in NOD/SCID mouse assessed as inhibition of Chk1 phosphorylation at 50 to 100 mg/kg, po administered twice a day for 30 days by Western blot analysis

Organism: Homo sapiens

Cell type: LoVo

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
424.514.404.40