Basic Information
ID: ALA5159488
Type: Binding
Description: Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysis
Format: BAO_0000357
Organism: Trypanosoma cruzi
Target: Cruzipain(ALA3563)
Document: ALA5154751
Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5159488
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 592.78 | 2.80 | 2.80 |
| 692.90 | 3.69 | 3.69 |
| 690.89 | 3.44 | 3.44 |
| 730.95 | 4.37 | 4.37 |
| 730.95 | 4.37 | 4.37 |
| 771.02 | 5.29 | 5.29 |
| 726.92 | 3.88 | 3.88 |
| 740.95 | 4.27 | 4.27 |
| 732.97 | 4.61 | 4.61 |
| 783.03 | 5.30 | 5.30 |
| 732.97 | 4.61 | 4.61 |
| 773.03 | 5.54 | 5.54 |
| 801.09 | 6.17 | 6.17 |
| 781.01 | 5.20 | 5.20 |
| 820.09 | 6.49 | 6.49 |
| 843.08 | 6.11 | 6.11 |
| 850.11 | 6.49 | 6.49 |
| 886.07 | 7.26 | 7.26 |
| 818.07 | 6.24 | 6.24 |
| 845.10 | 6.36 | 6.36 |
| 888.09 | 7.50 | 7.50 |
| 154.21 | 1.70 | 1.70 |
| 848.10 | 6.25 | 6.25 |
| 868.13 | 7.39 | 7.39 |
| 870.15 | 7.64 | 7.64 |