Basic Information
ID: ALA5159662
Type: Functional
Description: Antagonist activity at human GPR84 expressed in HEK293 cells co-expressing Galpha16 assessed as reduction in 6-OAU induced intracellular calcium response preincubated for 10 mins followed by agonist addition and measured after 1 min by calcium mobilization assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5159662
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 250.19 | 3.24 | 3.24 |
| 421.45 | 2.23 | 2.23 |
| 378.43 | 2.02 | 2.02 |
| 510.62 | 8.67 | 8.67 |
| 572.53 | 8.72 | 8.72 |
| 235.31 | 4.22 | 4.22 |
| 528.52 | 7.71 | 7.71 |
| 530.50 | 7.68 | 7.68 |
| 596.60 | 8.46 | 8.46 |
| 472.41 | 7.86 | 7.86 |
| 656.65 | 8.48 | 8.48 |
| 632.58 | 8.74 | 8.74 |
| 564.60 | 9.06 | 9.06 |
| 605.44 | 9.75 | 9.75 |
| 524.49 | 8.48 | 8.48 |
| 552.54 | 8.30 | 8.30 |
| 572.53 | 8.72 | 8.72 |
| 528.43 | 6.58 | 6.58 |
| 605.44 | 9.75 | 9.75 |
| 656.65 | 8.48 | 8.48 |
| 306.28 | 3.76 | 3.76 |
| 472.41 | 7.86 | 7.86 |
| 504.41 | 7.73 | 7.73 |
| 572.53 | 8.72 | 8.72 |
| 632.58 | 8.74 | 8.74 |
| 596.60 | 8.46 | 8.46 |
| 564.60 | 9.06 | 9.06 |
| 564.60 | 9.06 | 9.06 |
| 536.55 | 8.45 | 8.45 |
| 572.53 | 8.72 | 8.72 |
| 652.71 | 10.02 | 10.02 |
| 480.48 | 7.47 | 7.47 |
| 605.44 | 9.75 | 9.75 |
| 605.44 | 9.75 | 9.75 |
| 528.59 | 9.10 | 9.10 |
| 656.65 | 8.48 | 8.48 |
| 572.53 | 8.72 | 8.72 |
| 624.65 | 9.24 | 9.24 |
| 514.56 | 8.45 | 8.45 |
| 632.58 | 8.74 | 8.74 |
| 596.60 | 8.46 | 8.46 |
| 572.53 | 8.72 | 8.72 |
| 632.58 | 8.74 | 8.74 |
| 500.47 | 7.33 | 7.33 |
| 572.53 | 8.72 | 8.72 |
| 372.29 | 5.55 | 5.55 |