Basic Information
ID: ALA5159692
Type: Binding
Description: Selectivity ratio of IC50 for antagonist activity at GPR120 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as reduction in TUG-891 induced intracellular calcium response preincubated for 10 mins followed by agonist addition and measured after 1 min by calcium mobilization assay to IC50 for antagonist activity at human GPR84 expressed in HEK293 cells co-expressing Galpha16 assessed as reduction in 6-OAU induced intracellular calcium response preincubated for 10 mins followed by agonist addition and measured after 1 min by calcium mobilization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5159692
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 378.43 | 2.02 | 2.02 |
| 605.44 | 9.75 | 9.75 |