Basic Information
ID: ALA5159712
Type: Binding
Description: Inhibition of N-terminal His/GST-tagged human LSD1 (172 to 852 residues) expressed in expressed in baculovirus infected insect cells using biotinylated H3K4Me2 peptide as substrate by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5159712
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 364.49 | 3.74 | 3.74 |
| 411.57 | 2.88 | 2.88 |
| 437.61 | 3.42 | 3.42 |
| 411.57 | 3.15 | 3.15 |
| 441.60 | 2.89 | 2.89 |
| 349.50 | 1.45 | 1.45 |
| 341.50 | 2.82 | 2.82 |
| 501.70 | 4.80 | 4.80 |
| 405.52 | 3.48 | 3.48 |
| 410.58 | 4.46 | 4.46 |
| 425.60 | 3.40 | 3.40 |
| 446.02 | 3.54 | 3.54 |
| 363.53 | 1.84 | 1.84 |
| 355.53 | 3.21 | 3.21 |
| 404.54 | 4.08 | 4.08 |
| 461.63 | 4.04 | 4.04 |
| 425.60 | 3.27 | 3.27 |
| 403.47 | 2.34 | 2.34 |
| 417.62 | 3.16 | 3.16 |
| 327.47 | 2.43 | 2.43 |
| 479.57 | 3.90 | 3.90 |
| 447.60 | 4.15 | 4.15 |
| 383.52 | 2.10 | 2.10 |
| 443.57 | 4.57 | 4.57 |
| 375.52 | 3.33 | 3.33 |
| 389.54 | 3.26 | 3.26 |
| 487.67 | 4.55 | 4.55 |
| 425.60 | 3.27 | 3.27 |
| 355.53 | 3.07 | 3.07 |