Basic Information
ID: ALA5159800
Type: Binding
Description: Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu Leu-Val-Tyr-AMC as substrate preincubated for 15 mins followed by substrate addition measured by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5159800
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.25 | ||
| 724.33 | 4.51 | 4.51 |
| 711.91 | 4.70 | 4.70 |
| 723.92 | 4.67 | 4.67 |
| 723.92 | 4.67 | 4.67 |
| 763.00 | 5.62 | 5.62 |
| 772.39 | 5.87 | 5.87 |
| 737.95 | 4.70 | 4.70 |
| 697.88 | 4.36 | 4.36 |
| 709.89 | 4.07 | 4.07 |
| 709.89 | 3.78 | 3.78 |
| 732.33 | 4.79 | 4.79 |
| 750.99 | 5.69 | 5.69 |
| 697.88 | 4.36 | 4.36 |
| 725.94 | 4.72 | 4.72 |
| 771.40 | 5.96 | 5.96 |
| 711.91 | 4.38 | 4.38 |
| 710.88 | 3.46 | 3.46 |
| 737.95 | 4.56 | 4.56 |
| 736.96 | 5.30 | 5.30 |
| 771.40 | 5.96 | 5.96 |
| 766.98 | 5.31 | 5.31 |
| 737.95 | 4.70 | 4.70 |
| 743.97 | 4.76 | 4.76 |
| 758.36 | 5.43 | 5.43 |
| 754.95 | 5.44 | 5.44 |
| 771.40 | 5.96 | 5.96 |
| 725.94 | 4.72 | 4.72 |
| 723.92 | 4.09 | 4.09 |
| 746.35 | 4.82 | 4.82 |
| 737.95 | 4.70 | 4.70 |
| 711.91 | 4.38 | 4.38 |
| 748.97 | 5.23 | 5.23 |
| 737.95 | 4.70 | 4.70 |