Assay Report Card

Basic Information

ID: ALA5160167

Type: Binding

Description: Protac activity at VHL/SOS1 in human NCI-H358 cells assessed as SOS1 protein degradation pretreated with VHL ligand and MG132 at 1 uM followed by compound addition and measured after 24 hr by western blot analysis

Organism: Homo sapiens

Cell type: NCI-H358

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1051.82