Basic Information
ID: ALA5160616
Type: ADME
Description: Inhibition of CYP2D6 in rat liver microsomes at 100 uM using midazolam as substrate preincubated for 5 min followed by NADPH addition and measured after 40 mins by UHPLC-MS/MS analysis
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5160616
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 458.57 | 4.30 | 4.30 |