Basic Information
ID: ALA5160717
Type: Binding
Description: Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity at 2.5 uM by measuring adriamycin IC50 after 48 hrs by MTT assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: K562/A02
Target: P-glycoprotein 1(ALA4302)
Document: ALA5154779
Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity at 2.5 uM by measuring adriamycin IC50 after 48 hrs by MTT assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5160717
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 488.98 | 4.17 | 4.17 |