Basic Information
ID: ALA5160718
Type: Binding
Description: Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as fold reduction in adriamycin IC50 at 0.01 uM measured after 48 hrs by MTT assay relative to adriamycin IC50 alone
Format: BAO_0000219
Organism: Homo sapiens
Cell type: K562/A02
Target: P-glycoprotein 1(ALA4302)
Document: ALA5154779
Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as fold reduction in adriamycin IC50 at 0.01 uM measured after 48 hrs by MTT assay relative to adriamycin IC50 alone: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5160718
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 488.98 | 4.17 | 4.17 |