Basic Information
ID: ALA5160740
Type: Binding
Description: Reversal of BCRP-mediated multidrug resistance in dog MDCK-II-BCRP cells assessed as fold reduction in mitoxantrone IC50 at 1.25 uM measured after 48 hrs by MTT assay relative to mitoxantrone IC50 alone
Format: BAO_0000219
Organism: Canis lupus familiaris
Cell type: MDCK-II-BCRP
Target: Unchecked(ALA612545)
Document: ALA5154779
Reversal of BCRP-mediated multidrug resistance in dog MDCK-II-BCRP cells assessed as fold reduction in mitoxantrone IC50 at 1.25 uM measured after 48 hrs by MTT assay relative to mitoxantrone IC50 alone: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5160740
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 488.98 | 4.17 | 4.17 |