Basic Information
ID: ALA5160745
Type: Binding
Description: Inhibition of BCRP-mediated multidrug resistance in dog MDCK-II-BCRP cells assessed as mitoxantrone accumulation at 0.1 to 5 uM pretreated 1.5 hrs followed by treated with mitoxantrone measured after 4 hrs by flow cytometry analysis
Format: BAO_0000219
Organism: Canis lupus familiaris
Cell type: MDCK-II-BCRP
Target: Unchecked(ALA612545)
Document: ALA5154779
Inhibition of BCRP-mediated multidrug resistance in dog MDCK-II-BCRP cells assessed as mitoxantrone accumulation at 0.1 to 5 uM pretreated 1.5 hrs followed by treated with mitoxantrone measured after 4 hrs by flow cytometry analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5160745
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 488.98 | 4.17 | 4.17 |