Basic Information
ID: ALA5160772
Type: Binding
Description: Inhibition of P-gp in human Caco-2 cells assessed as reduction in basal to apical transport of paclitaxel at 5 uM measured as apparent permeability after 180 mins by LC-MS/MS analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Caco-2
Target: P-glycoprotein 1(ALA4302)
Document: ALA5154779
Inhibition of P-gp in human Caco-2 cells assessed as reduction in basal to apical transport of paclitaxel at 5 uM measured as apparent permeability after 180 mins by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5160772
Papp
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 488.98 | 4.17 | 4.17 |