Basic Information
ID: ALA5160803
Type: Functional
Description: Antiinflammatory activity in PMA-differentiated and LPS-stimulated human THP-1 cell model assessed as inhibition of NLRP3 inflammasome-driven IL-1beta production at 15 uM incubated for 24 hrs followed by LPS stimulation for 3 hrs and ATP addition for 1 hr by ELISA
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA5160803
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 166.22 | 2.40 | 2.40 |
| 280.26 | 3.42 | 3.42 |
| 772.82 | 7.71 | 7.71 |
| 200.28 | 0.82 | 0.82 |
| 609.73 | 4.59 | 4.59 |
| 255.25 | 3.25 | 3.25 |