Basic Information
ID: ALA5160887
Type: Binding
Description: Protac activity at VHL/EGFR L858R/T790M mutant (unknown origin) assessed as inhibition of EGFR incubated for 40 mins in presence of ATP by Kinase Glo luminescence assay
Format: BAO_0000224
Organism: Homo sapiens
Target: VHL/EGFR(ALA4523998)
Document: ALA5154782
Protac activity at VHL/EGFR L858R/T790M mutant (unknown origin) assessed as inhibition of EGFR incubated for 40 mins in presence of ATP by Kinase Glo luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5160887
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 499.62 | 4.51 | 4.51 |
| 1134.42 | ||
| 1146.43 | ||
| 537.67 | 4.41 | 4.41 |
| 1183.45 | ||
| 523.65 | 4.02 | 4.02 |
| 1150.46 |