Protac activity at VHL/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as EGFR degradation at 30 nM incubated for 24 hrs followed by replace...

Basic Information

ID: ALA5160902

Type: Binding

Description: Protac activity at VHL/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as EGFR degradation at 30 nM incubated for 24 hrs followed by replacement with fresh medium without compound measured after 48 hrs by Western blot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: NCI-H1975

Target:  VHL/EGFR(ALA4523998)

Document:  ALA5154782

Protac activity at VHL/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as EGFR degradation at 30 nM incubated for 24 hrs followed by replacement with fresh medium without compound measured after 48 hrs by Western blot analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1092.43