ID: ALA5160903
Type: Binding
Description: Protac activity at VHL/P-EGFR L858R/T790M mutant in human HCC827 cells assessed as EGFR degradation at 30 nM incubated for 24 hrs followed by replacement with fresh medium without compound measured after 48 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HCC827
Target: VHL/EGFR(ALA4523998)
Document: ALA5154782
Protac activity at VHL/P-EGFR L858R/T790M mutant in human HCC827 cells assessed as EGFR degradation at 30 nM incubated for 24 hrs followed by replacement with fresh medium without compound measured after 48 hrs by Western blot analysis: 1
Bioactivity
Activity Types for Assay ALA5160903
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
1092.43 |