Protac activity at VHL/P-EGFR L858R/T790M mutant in human HCC827 cells assessed as EGFR degradation at 30 nM incubated for 24 hrs followed by replacem...

Basic Information

ID: ALA5160903

Type: Binding

Description: Protac activity at VHL/P-EGFR L858R/T790M mutant in human HCC827 cells assessed as EGFR degradation at 30 nM incubated for 24 hrs followed by replacement with fresh medium without compound measured after 48 hrs by Western blot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HCC827

Target:  VHL/EGFR(ALA4523998)

Document:  ALA5154782

Protac activity at VHL/P-EGFR L858R/T790M mutant in human HCC827 cells assessed as EGFR degradation at 30 nM incubated for 24 hrs followed by replacement with fresh medium without compound measured after 48 hrs by Western blot analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1092.43