Basic Information
ID: ALA5160913
Type: Functional
Description: Antiproliferative activity against human NCI-H1975 cells expressing EGFR L858R/T790M mutant assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Organism: Homo sapiens
Cell type: NCI-H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA5160913
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 468.61 | 5.18 | 5.18 |
| 499.62 | 4.51 | 4.51 |
| 538.66 | 3.81 | 3.81 |
| 1097.44 | ||
| 1092.43 | ||
| 539.69 | 4.64 | 4.64 |
| 545.65 | 5.18 | 5.18 |
| 1050.35 | ||
| 1026.32 | ||
| 1134.42 | ||
| 1121.43 | ||
| 537.67 | 4.41 | 4.41 |
| 1078.40 | ||
| 1092.43 | ||
| 1146.43 | ||
| 1101.34 | ||
| 523.65 | 4.02 | 4.02 |
| 1125.50 | ||
| 537.67 | 4.41 | 4.41 |
| 1171.48 | ||
| 537.67 | 4.41 | 4.41 |
| 1139.40 | ||
| 1107.40 | ||
| 1050.35 | ||
| 1094.44 | ||
| 1026.32 | ||
| 1154.50 | ||
| 1183.45 | ||
| 523.65 | 4.02 | 4.02 |
| 1150.46 | ||
| 1126.44 | ||
| 1092.43 | ||
| 1168.52 | ||
| 1153.51 | ||
| 1064.37 |