Basic Information
ID: ALA5160917
Type: Binding
Description: Protac activity at VHL/EGFR L858R/T790M mutant in human HCC827 cells assessed as induction of EGFR degradation at 100 nM incubated for 24 hrs by Western blot analysis relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HCC827
Target: VHL/EGFR(ALA4523998)
Document: ALA5154782
Protac activity at VHL/EGFR L858R/T790M mutant in human HCC827 cells assessed as induction of EGFR degradation at 100 nM incubated for 24 hrs by Western blot analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5160917
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1097.44 | ||
| 1026.32 | ||
| 1125.50 | ||
| 1171.48 | ||
| 1026.32 | ||
| 1154.50 | ||
| 1150.46 | ||
| 1168.52 | ||
| 1153.51 |