Basic Information
ID: ALA5160980
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsomes using as midazolam substrate incubated for 10 min followed by NADPH addition for 10 mins by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5160980
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.49 | 4.74 | 4.74 |
| 435.50 | 5.35 | 5.35 |