Basic Information
ID: ALA5161149
Type: ADME
Description: Metabolic stability in rat liver microsomes assessed as parent compound remaining at 0.5 uM incubated for 10 mins in presence of NADPH by LC-MS/MS analysis
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5161149
Stability
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 341.46 | 3.77 | 3.77 |
| 357.45 | 3.47 | 3.47 |
| 397.52 | 4.95 | 4.95 |
| 349.43 | 4.53 | 4.53 |
| 352.44 | 3.33 | 3.33 |
| 358.44 | 3.46 | 3.46 |
| 372.47 | 3.77 | 3.77 |
| 388.47 | 3.47 | 3.47 |
| 413.42 | 4.62 | 4.62 |
| 382.46 | 3.94 | 3.94 |
| 354.28 | 4.59 | 4.59 |
| 388.47 | 3.47 | 3.47 |
| 392.89 | 4.12 | 4.12 |
| 375.44 | 4.21 | 4.21 |
| 367.42 | 4.61 | 4.61 |
| 425.45 | 4.75 | 4.75 |
| 426.44 | 4.48 | 4.48 |
| 425.45 | 5.09 | 5.09 |
| 411.42 | 4.36 | 4.36 |
| 410.47 | 4.33 | 4.33 |
| 313.45 | 3.90 | 3.90 |
| 372.47 | 3.77 | 3.77 |
| 385.51 | 4.69 | 4.69 |
| 409.45 | 4.87 | 4.87 |
| 372.47 | 3.77 | 3.77 |
| 383.45 | 3.34 | 3.34 |
| 395.43 | 4.48 | 4.48 |
| 361.87 | 4.11 | 4.11 |
| 391.90 | 4.72 | 4.72 |
| 392.89 | 4.12 | 4.12 |
| 363.41 | 3.74 | 3.74 |
| 366.47 | 3.72 | 3.72 |
| 359.45 | 3.99 | 3.99 |
| 379.86 | 4.25 | 4.25 |
| 349.43 | 4.53 | 4.53 |
| 369.84 | 4.88 | 4.88 |
| 363.41 | 3.74 | 3.74 |
| 372.47 | 3.77 | 3.77 |
| 387.48 | 3.56 | 3.56 |
| 345.42 | 3.60 | 3.60 |
| 358.44 | 3.46 | 3.46 |
| 371.48 | 4.38 | 4.38 |
| 385.40 | 5.16 | 5.16 |
| 408.45 | 4.40 | 4.40 |
| 407.46 | 5.01 | 5.01 |
| 441.45 | 4.97 | 4.97 |
| 408.45 | 4.40 | 4.40 |
| 391.46 | 4.79 | 4.79 |
| 333.86 | 4.25 | 4.25 |
| 361.42 | 3.82 | 3.82 |
| 392.89 | 4.12 | 4.12 |