Basic Information
ID: ALA5161275
Type: Binding
Description: Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced Ca2+ influx at 10 uM incubated for 30 mins by FLIPR method
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA5161275
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 429.24 | 4.26 | 4.26 |
| 377.51 | 5.80 | 5.80 |
| 391.54 | 6.30 | 6.30 |
| 446.35 | 6.08 | 6.08 |
| 391.54 | 6.30 | 6.30 |
| 435.45 | 6.34 | 6.34 |
| 385.44 | 5.46 | 5.46 |
| 431.48 | 6.51 | 6.51 |
| 383.90 | 5.83 | 5.83 |
| 409.53 | 6.44 | 6.44 |
| 428.36 | 5.94 | 5.94 |
| 418.50 | 5.87 | 5.87 |
| 385.44 | 5.46 | 5.46 |
| 428.90 | 5.74 | 5.74 |
| 384.89 | 5.23 | 5.23 |
| 379.49 | 5.19 | 5.19 |
| 385.44 | 5.46 | 5.46 |
| 417.46 | 6.20 | 6.20 |
| 383.90 | 5.83 | 5.83 |
| 385.44 | 5.46 | 5.46 |
| 391.54 | 6.30 | 6.30 |
| 435.45 | 6.34 | 6.34 |
| 383.90 | 5.83 | 5.83 |
| 435.45 | 6.34 | 6.34 |
| 452.79 | 7.14 | 7.14 |
| 391.54 | 6.10 | 6.10 |
| 435.45 | 6.34 | 6.34 |
| 446.35 | 6.08 | 6.08 |
| 397.93 | 6.14 | 6.14 |
| 452.79 | 7.14 | 7.14 |
| 400.51 | 5.73 | 5.73 |
| 428.36 | 5.94 | 5.94 |
| 428.36 | 5.94 | 5.94 |
| 383.90 | 5.83 | 5.83 |
| 405.57 | 6.48 | 6.48 |
| 400.51 | 5.73 | 5.73 |
| 397.48 | 5.33 | 5.33 |
| 367.45 | 5.32 | 5.32 |
| 384.89 | 5.23 | 5.23 |
| 385.44 | 5.46 | 5.46 |
| 391.54 | 6.30 | 6.30 |
| 367.45 | 5.32 | 5.32 |
| 394.46 | 5.09 | 5.09 |
| 412.45 | 5.23 | 5.23 |
| 379.49 | 5.19 | 5.19 |
| 383.90 | 5.83 | 5.83 |
| 418.35 | 6.49 | 6.49 |
| 397.48 | 5.33 | 5.33 |
| 446.35 | 6.08 | 6.08 |
| 379.49 | 5.19 | 5.19 |
| 402.88 | 5.37 | 5.37 |
| 418.50 | 5.87 | 5.87 |
| 401.89 | 5.97 | 5.97 |
| 401.89 | 5.97 | 5.97 |
| 402.88 | 5.37 | 5.37 |
| 383.90 | 5.83 | 5.83 |
| 385.44 | 5.46 | 5.46 |
| 435.45 | 6.34 | 6.34 |
| 417.46 | 6.20 | 6.20 |
| 409.51 | 5.20 | 5.20 |
| 417.46 | 6.20 | 6.20 |
| 428.36 | 5.94 | 5.94 |
| 428.36 | 5.94 | 5.94 |
| 417.46 | 6.20 | 6.20 |
| 428.36 | 5.94 | 5.94 |
| 367.45 | 5.32 | 5.32 |
| 367.45 | 5.32 | 5.32 |
| 379.49 | 5.19 | 5.19 |
| 394.46 | 5.09 | 5.09 |
| 428.90 | 5.74 | 5.74 |
| 435.45 | 6.34 | 6.34 |
| 377.51 | 5.80 | 5.80 |
| 377.51 | 5.80 | 5.80 |
| 367.45 | 5.32 | 5.32 |
| 377.51 | 5.80 | 5.80 |
| 367.45 | 5.32 | 5.32 |
| 408.48 | 5.40 | 5.40 |
| 423.56 | 6.62 | 6.62 |
| 367.45 | 5.32 | 5.32 |
| 401.89 | 5.97 | 5.97 |
| 417.46 | 6.20 | 6.20 |
| 391.54 | 6.10 | 6.10 |
| 417.46 | 6.20 | 6.20 |