Basic Information
ID: ALA5161378
Type: Binding
Description: Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation incubated for 30 mins followed by A2318 stimulation in presence of IBMX for 1 hr by HTRF assay relative to control
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5161378
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 379.46 | 3.38 | 3.38 |
| 351.41 | 2.64 | 2.64 |
| 399.45 | 3.75 | 3.75 |
| 353.38 | 2.09 | 2.09 |
| 355.37 | 2.53 | 2.53 |
| 365.44 | 3.20 | 3.20 |
| 353.38 | 2.09 | 2.09 |
| 367.41 | 2.48 | 2.48 |
| 337.38 | 2.39 | 2.39 |
| 351.41 | 2.70 | 2.70 |
| 339.36 | 1.78 | 1.78 |
| 341.35 | 2.22 | 2.22 |
| 324.34 | 1.47 | 1.47 |
| 261.29 | 0.78 | 0.78 |
| 351.41 | 2.70 | 2.70 |
| 363.42 | 2.96 | 2.96 |
| 341.35 | 2.22 | 2.22 |
| 351.41 | 2.64 | 2.64 |
| 351.41 | 2.32 | 2.32 |
| 366.43 | 2.14 | 2.14 |
| 341.35 | 2.22 | 2.22 |
| 337.38 | 2.39 | 2.39 |
| 379.46 | 3.38 | 3.38 |
| 323.36 | 2.08 | 2.08 |
| 383.41 | 2.06 | 2.06 |
| 313.32 | 1.67 | 1.67 |
| 355.37 | 2.15 | 2.15 |
| 399.45 | 3.75 | 3.75 |
| 369.45 | 2.80 | 2.80 |
| 391.35 | 3.10 | 3.10 |
| 402.25 | 2.84 | 2.84 |
| 355.37 | 2.53 | 2.53 |
| 351.41 | 2.64 | 2.64 |
| 357.80 | 2.73 | 2.73 |
| 337.38 | 2.39 | 2.39 |
| 357.80 | 2.73 | 2.73 |