Assay Report Card

Basic Information

ID: ALA5161739

Type: ADME

Description: Transactivation of human PXR transfected in HepG2 cells assessed as CYP450 induction by measuring fold activation at 10 uM by luciferase reporter gene assay

Organism: Homo sapiens

Cell type: HepG2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
505.295.195.19
483.885.575.57
484.874.964.96
482.896.096.09
526.325.735.73
484.874.964.96
429.915.025.02
466.885.245.24
481.875.625.62
484.875.535.53
430.894.994.99
498.905.275.27
460.845.085.08