Basic Information
ID: ALA5161752
Type: Functional
Description: Invivo inhibition of MAT2A in human HCT116-MTAP null cells xenografted po dosed nu/nu mouse model assessed as plasma exposure required for reduction in brain SAM level
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA5161752
fIC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 505.29 | 5.19 | 5.19 |
| 484.87 | 4.96 | 4.96 |
| 430.89 | 4.99 | 4.99 |