Basic Information
ID: ALA5161892
Type: ADME
Description: Inhibition of CYP2C19 in human liver microsome at 10 uM using S-mephenytoin as substrate incubated for 10 mins in presence of NADPH cofactor by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5161892
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 513.59 | 4.98 | 4.98 |
| 497.60 | 5.74 | 5.74 |
| 499.57 | 4.59 | 4.59 |
| 511.62 | 6.13 | 6.13 |