Assay Report Card

Basic Information

ID: ALA5162079

Type: Binding

Description: Inhibition of DOT1L in human OCI-AML5 cells assessed as decrease in H3K79 methylation at 1 to 10 uM using histone H3 as substrate incubated for 3 days by immunoblotting assay

Organism: Homo sapiens

Cell type: OCI-AML5

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
562.723.323.32
559.764.434.43