Basic Information
ID: ALA5162082
Type: Binding
Description: Inhibition of DOT1L in human OCI-AML5 cells assessed as decrease in H3K79 methylation at 1 to 10 uM using histone H3 as substrate incubated for 5 days by immunoblotting assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: OCI-AML5
Target: Histone-lysine N-methyltransferase, H3 lysine-79 specific(ALA1795117)
Document: ALA5154806
Inhibition of DOT1L in human OCI-AML5 cells assessed as decrease in H3K79 methylation at 1 to 10 uM using histone H3 as substrate incubated for 5 days by immunoblotting assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5162082
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 562.72 | 3.32 | 3.32 |
| 559.76 | 4.43 | 4.43 |