Basic Information
ID: ALA5162231
Type: Binding
Description: Binding affinity to human CXCR2 expressed in human U87 cells assessed as inhibition of CXCL8 AF647-induced calcium response incubated for 10 mins followed by addition of CXCL8 AF647 measured by FLIPR Tetra system method
Organism: Homo sapiens
Cell type: U87
Activity Charts
Bioactivity
Activity Types for Assay ALA5162231
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.45 | 3.03 | 3.03 |
| 367.45 | 4.05 | 4.05 |
| 352.37 | 2.11 | 2.11 |
| 362.40 | 3.39 | 3.39 |
| 367.45 | 4.05 | 4.05 |
| 350.39 | 3.32 | 3.32 |
| 350.39 | 3.32 | 3.32 |
| 350.39 | 3.09 | 3.09 |
| 362.40 | 3.39 | 3.39 |
| 362.40 | 3.39 | 3.39 |
| 368.43 | 3.45 | 3.45 |
| 352.37 | 2.98 | 2.98 |
| 366.44 | 2.49 | 2.49 |
| 361.42 | 3.99 | 3.99 |
| 366.44 | 2.49 | 2.49 |
| 351.38 | 2.72 | 2.72 |