Basic Information
ID: ALA5162235
Type: Binding
Description: Induction of STING dependent immune response in human wild type THP1-Dual cells co-expressing ISRE reporter assessed as normalized luciferase gene expression by measuring relative luciferase units at 50 uM incubated for 24 hrs by QUANTI Luc based microplate reader method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP1-Dual
Target: Stimulator of interferon genes protein(ALA4523377)
Document: ALA5154810
Induction of STING dependent immune response in human wild type THP1-Dual cells co-expressing ISRE reporter assessed as normalized luciferase gene expression by measuring relative luciferase units at 50 uM incubated for 24 hrs by QUANTI Luc based microplate reader method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5162235
RLU
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 849.95 | 2.35 | 2.35 |
| 678.76 | 2.46 | 2.46 |
| 674.42 | -2.34 | -2.34 |
| 432.48 | 2.07 | 2.07 |
| 513.60 | 3.23 | 3.23 |
| 499.57 | 2.74 | 2.74 |
| 469.55 | 2.73 | 2.73 |
| 399.46 | 1.18 | 1.18 |
| 779.86 | 3.13 | 3.13 |
| 524.58 | 4.17 | 4.17 |
| 535.61 | 2.17 | 2.17 |
| 477.53 | 1.85 | 1.85 |
| 523.52 | 3.44 | 3.44 |
| 495.58 | 3.38 | 3.38 |
| 505.58 | 2.16 | 2.16 |
| 537.54 | 3.93 | 3.93 |
| 497.60 | 3.61 | 3.61 |
| 916.02 | 4.13 | 4.13 |
| 383.46 | 1.65 | 1.65 |
| 441.49 | 3.29 | 3.29 |
| 505.58 | 2.26 | 2.26 |
| 511.63 | 3.95 | 3.95 |
| 708.78 | 4.99 | 4.99 |
| 511.58 | 3.00 | 3.00 |
| 440.46 | 3.00 | 3.00 |
| 497.60 | 3.78 | 3.78 |
| 440.46 | 3.87 | 3.87 |
| 467.57 | 2.85 | 2.85 |
| 472.43 | 2.87 | 2.87 |
| 758.64 | 4.07 | 4.07 |
| 533.64 | 3.04 | 3.04 |
| 702.78 | 3.95 | 3.95 |
| 491.55 | 4.44 | 4.44 |
| 487.56 | 3.12 | 3.12 |
| 469.55 | 2.83 | 2.83 |
| 425.49 | 1.83 | 1.83 |
| 486.45 | 3.36 | 3.36 |
| 879.98 | 4.70 | 4.70 |
| 680.73 | 4.82 | 4.82 |
| 390.40 | 2.71 | 2.71 |
| 488.55 | 2.52 | 2.52 |
| 483.57 | 3.22 | 3.22 |
| 519.61 | 2.65 | 2.65 |
| 694.71 | 6.06 | 6.06 |