Basic Information
ID: ALA5162239
Type: Binding
Description: Agonist activity at STING in human wild-type THP1-Dual cells co-expressing ISRE reporter assessed as IRF-mediated immune response incubated for 24 hrs by QUANTI Luc based microplate reader method
Organism: Homo sapiens
Cell type: THP1-Dual
Activity Charts
Bioactivity
Activity Types for Assay ALA5162239
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 849.95 | 2.35 | 2.35 |
| 678.76 | 2.46 | 2.46 |
| 674.42 | -2.34 | -2.34 |
| 432.48 | 2.07 | 2.07 |
| 513.60 | 3.23 | 3.23 |
| 499.57 | 2.74 | 2.74 |
| 399.46 | 1.18 | 1.18 |
| 779.86 | 3.13 | 3.13 |
| 535.61 | 2.17 | 2.17 |
| 505.58 | 2.16 | 2.16 |
| 497.60 | 3.61 | 3.61 |
| 916.02 | 4.13 | 4.13 |
| 505.58 | 2.26 | 2.26 |
| 511.58 | 3.00 | 3.00 |
| 467.57 | 2.85 | 2.85 |
| 758.64 | 4.07 | 4.07 |
| 487.56 | 3.12 | 3.12 |
| 469.55 | 2.83 | 2.83 |
| 879.98 | 4.70 | 4.70 |
| 483.57 | 3.22 | 3.22 |
| 519.61 | 2.65 | 2.65 |